Evaluation of The Mean Percentages of The Peripheral Blood Gamma Delta T Lymphocytes in The Healthy Subjects and Celiac Patients in Isfahan

Abstract

Background :

An elevation in the mean percentages of the gamma delta T lymphocytes per total T cells in the epithelium of the small intestine has a diagnostic value for celiac disease.  This study aimed to measure the percentages of the peripheral blood gamma delta T lymphocytes in the adults' celiac disease and healthy controls.

Materials and Methods:

In this case-control study the absolute numbers of the peripheral blood lymphocytes obtained from the controls (n = 21) and celiac patients (n = 15) were studied, Using a cell counter. The proportions of the gamma-delta T lymphocytes were evaluated by the flow cytometer method.

Results:

The results showed that there was not significant  I difference in the percentages of the gamma-delta T lymphocytes between celiac patients and healthy individuals ( P value= 0.84 ).

Conclusions:

Collectively, the data show that the percentages of the peripheral blood gamma delta T lymphocytes could not be helpful for celiac disease diagnosis.