Prevalence of Peptic Ulcer in Iran using the meta-analysis and systematic review

Hamed Tavan, Kourosh Sayehmiri



Peptic ulcer is common and symptoms such as epigastria pain and heartburn, the results of various studies and aim of study was to evaluate the prevalence of gastric ulcers in the systematic review and meta-analysis is a method.

Materials and methods:

6 Iranian papers in the range of 2002 to 2012 are selected using valid keywords in the SID, Goggle scholar and Elsevier databases and heterogeneously of the sample are obtained using the I2 index.


In this study, the total number of data, 751 people with an average of 125 in each study 6 article in the meta-analysis, the final entered the prevalence of gastric ulcers in women by 30% with 95% confidence intervals (41% -19%) and the level significant P = 0.000 and index I2 89.6% incidence of Peptic ulcers in men and 60% with 95% confidence intervals (67% -53%) and a significance level of P = 0.051 and index I2 54.7% and the incidence of Peptic ulcers generally 41 % with 95% confidence intervals (47% -36%) and a significance level of P =0.222 and index I2 28.4% is calculated.


The prevalence of Peptic ulcers in Iran (41%) and the rest of the world (6% to 15%) and the rate is increasing with the increase in the incidence in men (60%) and among women (30%), which indicates that more men than women suffer from stomach ulcers are probably a major reason it is recommended to quit smoking by men is done by them.


Peptic ulcers, Iran, Prevalence, Meta-analysis, Systematic review

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- Ghahramani R, Sadoogh Abbasian A, Shafaee S . Prevelence of Celiac Disease in Patients with Different Types of Dyspepsia. Journal of Isfahan Medical School 2009:27(93):63-68

- Kalantari H, Nauruan M. Prevalence of Peptic Ulcer Versus Non Ulcer Dyspepsia in Patients which were admitted for Endoscopy . Journal of Isfahan Medical School 2011. 28(118):44-53

- Abdollahi L , Zolfaghari MR, Amini M , Salehi R. The Relation between Microalbuminuria and Helicobacter Pylori VacA Gene in Type 2 Diabetic Patients, Isfahan, Iran. Journal of Isfahan Medical 2012:30(179):33-38

- Ehteram H , Mesdaghinia E , Mazoochi T. Helicobacter Pylori and Hyperemesis Gravidarum. Journal of Arak University of Medical Sciences. 2009: 12(1): 1-7

- Talebi Bezmin Abadi A, Mohabati Mobarez A, Taghvaei T. An investigation of the prevalence of iceA genotypes in Helicobacter pylori strains isolated from peptic ulcer patients in Sari (2008). Arak Medical University Journal (AMUJ). 2010; 13(3): 84-90

- Goudarzi H, Rezaee H , Rafizadeh M , Taghavi A, Mirsamadi E. The frequency of cagA gene of H.pylori isolated from biopsy specimen in Tehran during 2008-2010. Arak Medical University Journal (AMUJ). 2012; 15(64): 42-48.

- Karami L, Majd A , Mehrabian S , Nabiuni M , Irian S, SalehiM. Antimutagenic effects of ethanol and aqueous extracts of Avicennia marina leaves on Salmonella typhimurium TA100 bacterium. Arak Medical University Journal (AMUJ). 2013; 15(67): 68-76

- Mousavi F , Rahnema M , Heydarieh N, Tajabadi Ebrahimi M. The effect of Iranian native Lactobacillus pentosus on healing of gastric ulcers in male Wister rats. Arak Medical University Journal (AMUJ). 2013; 16(71): 81-90

- Salemi Z, Kamali Pooya S, Ghasemi M. Secretor status and some risk factors in duodenal ulcer, gastric ulcer, and gastric cancer. Arak Medical University Journal (AMUJ). 2013; 16(72): 45-51

- Fazli D, Davarpanah Y , Amini B. Effects of Examination Stress on Plasma Levels of Cortisol And Hypertension.Scientific Journal of Ilam University of Medical Science5 Jan 2010: 14(46):21-28

- Esmailnasab N , Taymoori P , Darabi F . COMPARISON OF QUALITY OF LIFE 3 AND 9 MONTHS AFTER SURGERY IN PATIENTS WITH GASTROINTESTINAL CANCER. The Journal of Urmia University of Medical Sciences. 2013: 24(4):21-26

-.Hajagamohammadi AA, Sheikholslami H, Esmaeili R. Prevalence of Helicobacter Pylori infection in different endoscopic lesions of patients in Qazvin Bouali Sina hospital(2002). The Journal of Qazvin University of Medical Sciences 2005. 9(36):68-72

-Vahidi Sh, Azadegan M, Shakeri A. Comparison of cytology and histopathology in the diagnosis of Helicobacter pylori infection in contact with the stomach biopsy specimens, Journal of the Faculty of Medicine, University of Medical Sciences and Health Services martyr Beheshti2002. 26(4):241-243

-Vafaie B, Golabi J. Surveying the association between life stresses and gastrointestinal diseases (peptic ulcer) Journal of the Faculty of Medicine, University of Medical Sciences and Health Services martyr Beheshti 2004. 28(4):285-289

- Shirazi MH, Ghasemi A, Khoramizadeh MR, Ebrahimi N, Hosaeini M, Sadeghifard N. Detection of cagA gene in H. pylori strains isolated from patients with NUD, peptic ulcers and cancer by PCR. Scientific Journal of Ilam University of Medical Sciences 2006. 14(3): 22-28

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